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  • Special |

    Cancer is a disease of the genome, caused by a cell's acquisition of somatic mutations in key cancer genes.

    Image: Nik Spencer/Nature

  • Special |

    The second phase of the 10-year NIH-funded Human Microbiome Project (HMP2) has reached its fruition in the form of a collection of studies addressing the role of the microbiota in inflammatory bowel disease, the onset of type 2 diabetes and in pregnancy and preterm birth.

    Image: AXS Studio

  • Special |

    An early career researcher’s guide to the working world of science, from Nature Careers.

    Image: SolStock/Getty

  • Special |

    Nature highlights the people, events and discoveries that made a difference through science in 2018.

    Image: Rogelio Moreno Gill/Nikon Small World 2018

  • Special |

    How is that a multitude of different molecules within a lipid envelope all come together to carry out the basic functions required to sustain organisms? Conventionally, biologists have worked from the top down to dissect how components in cells interact in their natural environment. But now technical advances are allowing researchers to take a different tack: using engineering principles to reconstruct biological processes from the bottom up. This special issue explores the potential and possible limits of bottom-up cell biology.

    Image: Nik Spencer/Nature

  • Special |

    Science moves forward by corroboration – when researchers verify others’ results. Science advances faster when people waste less time pursuing false leads. No research paper can ever be considered to be the final word, but there are too many that do not stand up to further study.

  • Special |

    From people with HIV selecting which trials get funded to smallholder farmers guiding weather monitoring, the people affected by research are increasingly getting involved in it. They are shaping how projects are conceived, supported, done, reviewed, disseminated and rated — as partners in research. This special issue looks at the promise and the pitfalls of research coproduction [for the societies, stakeholders and scientists now working shoulder to shoulder. As one advocate describes it: “It’s about getting everybody round the table so you’re valuing the knowledge everybody has.”

  • Special |

    Nature highlights the people, events and discoveries that made a difference through science in 2017.

    Image: Robert Lamberts/Plant & Food Research

  • Special |

    Image: Illustration by Jasiek Krzysztofiak/Nature; Images: Morphart Creation/Shutterstock, Jezper/Shutterst

  • Special |

    Scientists weathered a turbulent year, from political upheavals to the direct detection of gravity waves. Here, Nature highlights the people, events and discoveries that made a difference in 2016.

    Image: Igor Siwanowicz/Nikon Small World 2016

  • Special |

    Einstein published the first papers predicting the existence of gravitational waves — ripples in the fabric of space-time — almost a century ago. Physicists at the recently upgraded Laser Interferometer Gravitational-Wave Observatory (LIGO) have announced that they have measured these cosmic deformations, opening up a new field of gravitational-wave astronomy. Discover Nature’s coverage of the unfolding story and other gravitational-wave experiments, as well as everything you ever wanted to know about Einstein’s general theory of relativity.

    Image: MPI/Gravitational Physics/ITP Frankfurt/ZI Berlin