Collections

  • Nature Outline |

    Researchers are currently exploring a number of approaches to stimulating spinal-cord regeneration. Should they be successful, the lives of those with a spinal-cord injury will change once again.

    Image: Rosanna Wan
  • Nature Outline |

    Bone fractures that fail to heal with conventional treatment are known as non-union bone fractures. They cause prolonged pain and disability. Work is under way to improve the success rate of surgical repair and to accelerate the bone-healing process.

    Image: Rory Waudby-Tolley
  • Nature Outline |

    The worldwide rise in obesity and diabetes has led to a massive spike in the number of people with non-alcoholic fatty liver disease, which often advances to a more severe condition known as non-alcoholic steatohepatitis, and in some cases to fibrosis and cirrhosis. This Outline discusses new ways to diagnose and treat this progressive condition.

    Image: Andrew Khosravani
  • Nature Outline |

    When arteries become blocked, slowing or limiting blood flow, it can cause pain and sometimes the loss of a limb. Severe cases of critical limb ischaemia can be life threatening. Around 70% of patients are eligible for surgery; those who are not have had few options other than amputation. But regenerative therapies could change that.

    Image: Andrew Khosravani
  • Nature Outline |

    A burst eardrum — like a stubbed toe — is a common injury. Although ruptures can cause pain and hearing loss, most will heal naturally. For those that don’t, however, the only option is specialist surgery, but this is expensive and carries risks. It would be far better to try to stimulate the eardrum to heal itself, which is what tissue-engineering researchers think they have achieved.

    Image: Diana Gradinaru
  • Nature Outline |

    The eye is a remarkable organ, and the body makes a lot of effort to keep it clear to allow the best possible vision. When infection, injury or an inherited disease disrupts natural regeneration, this can result in pain, inflammation and potentially loss of vision. This Outline introduces the limbal stem cells that naturally regenerate the surface of the cornea, describes the surgical procedures that can help to regenerate the surface of the eye when it’s damaged and gives a flavour of future research directions.

    Image: Lucy Reading-Ikkanda
  • Nature Outline |

    Quantum computers are big news, each week brings reports of fresh advances in stability and power. But for many people, the quantum world is mysterious and confusing. In this Outline we explain the differences between classical and quantum computing, and introduce readers to the basic terminology; explore the challenges faced by researchers and engineers as they attempt to build a working quantum computer; and give a flavour of how quantum computers could revolutionize science and technology.

    Image: Visual Science