Featured
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News |
High-fat diets raise risk of obesity in offspring
Study in mice suggests that behaviour of parents influences health of children through 'epigenetic' inheritance.
- Linda Geddes
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News |
Fat mice provide clue to obesity-colon cancer puzzle
Study suggests stem-cell stimulation is behind obesity’s contribution to cancer risk.
- Heidi Ledford
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Research Highlights |
On–off switch for obesity
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Research Highlights |
Gastric surgery alters sweet tooth
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News & Views |
Light on leptin link to lipolysis
Cutting-edge experiments show that the hormone leptin, which is secreted by fat cells, promotes fat loss by activating the release of catecholamine signalling molecules from neurons wrapped around the fat cells.
- Johan Ruud
- & Jens C. Brüning
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News Explainer |
Low-fat diets have low impact
Large analysis finds that decades' worth of medical advice was misguided.
- Heidi Ledford
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Social Selection |
Dietary data under fire for being unreliable
Food guidelines should not be based on surveys of what people eat and drink, says report.
- Chris Woolston
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News |
Marijuana flips appetite switch in brain
Sudden attacks of 'the munchies' are triggered by a change in the hormone released by neurons.
- Boer Deng
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Article |
Global diets link environmental sustainability and human health
As incomes grow, diets change, with varying impacts on human health and the environment; here the links are examined and suggestions made for diets that both improve health and minimize environmental impacts.
- David Tilman
- & Michael Clark
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Outlook |
Public health: Society at large
The increasing prevalence of obesity is a worldwide phenomenon, affecting peoples from diverse cultural and economic backgrounds. By Tony Scully.
- Tony Scully
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Outlook |
Perspective: Tricks of the trade
Processed foods that dilute protein content subvert our appetite control systems, say Stephen J. Simpson and David Raubenheimer.
- Stephen J. Simpson
- & David Raubenheimer
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Outlook |
Perspective: Obesity is not a disease
The misguided urge to pathologize this condition reflects society's failure to come to terms with the need for prevention, says D. L. Katz.
- D. L. Katz
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Outlook |
Cell physiology: The changing colour of fat
The different functions of white, brown and beige fat might yield new targets in the fight against obesity and metabolic disease.
- Brian Owens
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Outlook |
Neuroscience: Dissecting appetite
A slew of new technologies are helping to map the neural circuits that control when, and how much, we eat.
- Bijal P. Trivedi
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Outlook |
Microbiome: A complicated relationship status
Nothing is simple about the links between the bacteria living in our guts and obesity.
- Sarah Deweerdt
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Outlook |
Heritability: The family roots of obesity
Scores of genes are implicated in obesity, but they cannot account for a family's predisposition to obesity. Are there other ways parents can influence their children?
- Cassandra Willyard
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Outlook |
Treatment: Marginal gains
Behavioural interventions work, but not for everyone, and weight regain is common. Are there better ways to treat obesity?
- Emily Anthes
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News & Views |
Malnutrition promotes rogue bacteria
Dietary lack of a single amino acid impairs intestinal immunity in mice, altering the guts microbial community and leaving it vulnerable to damage. The finding helps to explain how malnutrition favours gut inflammation. See Letter p.477
- Ana Izcue
- & Fiona Powrie
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Letter |
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
Mutations in angiotensin-converting enzyme 2 are shown to predispose mice to colitis as a consequence of neutral amino acid malabsorption and a change in the resident microbiota; these results could explain how protein malnutrition — affecting up to one billion people — leads to intestinal inflammation.
- Tatsuo Hashimoto
- , Thomas Perlot
- & Josef M. Penninger
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News & Views |
50 & 100 years ago
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Review Article |
Human nutrition, the gut microbiome and the immune system
- Andrew L. Kau
- , Philip P. Ahern
- & Jeffrey I. Gordon
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News |
Grants aim to fight malnutrition
Cash boost should help bring fortified rice and cassava to market.
- Anjali Nayar
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News |
Do gut bacteria worsen malnourishment?
Human microbiota could be behind why deficient diets leave only some children seriously ill.
- Nicola Jones
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News Explainer |
Is breast not best for babies?
New evidence contradicts World Health Organization breastfeeding advice.
- Natasha Gilbert
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Outlook |
History: The changing notion of food
The pioneers of nutrition research determined the energy content of food and also helped to overturn misconceptions about various diseases that plagued humankind.
- Ned Stafford
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Outlook |
Health: Edible advice
Diet-related illnesses are some of the biggest killers today. Can we tailor our food intake to prevent these diseases? Large international projects are underway to find out.
- Farooq Ahmed
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News Explainer |
US clamp-down on alcoholic energy drinks
Food and Drug Administration warns companies over drinks mixing alcohol with caffeine.
- Meredith Wadman
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Research Highlights |
Cognitive neuroscience: Vicious cycle of overeating
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Opinion |
Regulation must be revolutionized
Unjustified and impractical legal requirements are stopping genetically engineered crops from saving millions from starvation and malnutrition, says Ingo Potrykus.
- Ingo Potrykus
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Opinion |
Strategic body needed to beat food crises
The system that oversees global agriculture and food security needs an overhaul, says Joachim von Braun.
- Joachim von Braun