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| Open AccessChild wasting and concurrent stunting in low- and middle-income countries
An analysis of longitudinal cohort data across diverse populations suggests that the incidence of wasting between birth and 24 months is higher than previously thought, and highlights the role of seasonal factors that affect child growth.
- Andrew Mertens
- , Jade Benjamin-Chung
- & Pablo Penataro Yori
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Article
| Open AccessEarly-childhood linear growth faltering in low- and middle-income countries
A pooled analysis of longitudinal studies in low- and middle-income countries identifies the typical age of onset of linear growth faltering and investigates recurrent faltering in early life.
- Jade Benjamin-Chung
- , Andrew Mertens
- & Pablo Penataro Yori
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Article |
An organoid-based organ-repurposing approach to treat short bowel syndrome
In a rat model of short bowel syndrome, transplantation of small intestinal organoids into the colon partially restores intestinal function and improves survival—a proof of principle that organoid transplantation might have therapeutic benefit.
- Shinya Sugimoto
- , Eiji Kobayashi
- & Toshiro Sato
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Article
| Open AccessMapping child growth failure across low- and middle-income countries
High-resolution subnational mapping of child growth failure indicators for 105 low- and middle-income countries between 2000 and 2017 shows that, despite considerable progress, substantial geographical inequalities still exist in some countries.
- Damaris K. Kinyoki
- , Aaron E. Osgood-Zimmerman
- & Simon I. Hay
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Article
| Open AccessMapping child growth failure in Africa between 2000 and 2015
Geospatial estimates of child growth failure in Africa provide a baseline for measuring progress and a precision public health platform to target interventions to those populations with the greatest need.
- Aaron Osgood-Zimmerman
- , Anoushka I. Millear
- & Simon I. Hay
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News & Views |
Malnutrition promotes rogue bacteria
Dietary lack of a single amino acid impairs intestinal immunity in mice, altering the guts microbial community and leaving it vulnerable to damage. The finding helps to explain how malnutrition favours gut inflammation. See Letter p.477
- Ana Izcue
- & Fiona Powrie
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Letter |
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
Mutations in angiotensin-converting enzyme 2 are shown to predispose mice to colitis as a consequence of neutral amino acid malabsorption and a change in the resident microbiota; these results could explain how protein malnutrition — affecting up to one billion people — leads to intestinal inflammation.
- Tatsuo Hashimoto
- , Thomas Perlot
- & Josef M. Penninger
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News & Views |
50 & 100 years ago
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Review Article |
Human nutrition, the gut microbiome and the immune system
- Andrew L. Kau
- , Philip P. Ahern
- & Jeffrey I. Gordon
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News |
Grants aim to fight malnutrition
Cash boost should help bring fortified rice and cassava to market.
- Anjali Nayar
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News |
Do gut bacteria worsen malnourishment?
Human microbiota could be behind why deficient diets leave only some children seriously ill.
- Nicola Jones
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Opinion |
Regulation must be revolutionized
Unjustified and impractical legal requirements are stopping genetically engineered crops from saving millions from starvation and malnutrition, says Ingo Potrykus.
- Ingo Potrykus
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Opinion |
Strategic body needed to beat food crises
The system that oversees global agriculture and food security needs an overhaul, says Joachim von Braun.
- Joachim von Braun