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Three single-molecule methods promise to increase the time resolution of experiments, to allow better access to sparsely populated molecular states and to permit combinatorial high-throughput analysis.
Brainbow is a powerful genetic tool for multicolor labeling in mice with applications in fields including developmental biology and neuroanatomy. Now two groups have ported the approach to the fruit fly where it may have even greater impact.
Combining rule-based descriptions of biochemical reactions with agent-based computer simulation opens new avenues for exploring complex cellular processes.
Stimulated Raman scattering (SRS) microscopy is used to directly visualize lipids in cells and model organisms, and facilitates screening for genes involved in fat storage.
