News & Comment

The increasing impact of science on society calls for improved communication between scientists and the public via dedicated science media centers as well as nontraditional personal blogs.

Small RNA discovery and profiling efforts are dramatically reshaping fundamental concepts of how genes are regulated and are leading to new tools for studying gene function.

A new system capable of simultaneously monitoring thousands of individual polymerase enzymes enables accurate, multiplex DNA sequencing in real time.

Researchers develop a high-sensitivity, label-free imaging technology based on stimulated Raman scattering.

Kinetically bi-stable channelrhodopsin-2 variants enable sensitive, step-like and reversible photoexcitability in neurons.

Using time-lapse imaging, researchers study the potency and fate specification of live neural stem cells in culture.

By analyzing the data generated by the Northeast Structural Genomics Consortium (NESG), researchers quantified the physical properties that control protein crystallization.

The development of large-scale centralized biobanks raises the stakes in a familiar conversation on ethics in medical research and poses unique challenges to lawmakers that will require informed discussions between scientists and the public.

Methods to map active RNA polymerases and to assign transcripts to the sense or antisense strand are valuable additions to the functional analysis of the transcriptome.

Biobanking is gaining momentum as more and more patient samples and clinical information are being stored in facilities around the globe. New technology is helping everyone—from national efforts to smaller research laboratories—to process and track their biospecimen collections.

A device to cool localized areas of the zebra finch brain allows researchers to investigate how the timing of birdsong is controlled.

Scientists create a high-throughput platform for proteome-scale assessment of protein stability.

A new spin on a popular imaging technique allows researchers to accurately visualize tumors deep within the tissues of live mice.

The maturation of large-scale protein-protein interaction methodologies calls for improved methods to assess performance and data quality.

A new generation of brilliant X-ray laser sources will be coming online within the next few years. Researchers now show that using these lasers to determine the structures of single molecules should be possible.