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Using particle-by-particle assembly and adiabatic manipulation of disorder, low-entropy, strongly correlated quantum fluids of light are constructed, opening up new possibilities for the preparation of exotic phases of synthetic matter.
The tomato spotted wilt orthotospovirus nonstructural protein NSs interferes with phytohormone signalling in plants to compromise plant defences by interacting with plant TCP21—this effect of the viral protein is counteracted by the plant NLR immune receptor protein Tsw.
Msemburi et al. describe how the World Health Organization has estimated the excess mortality associated with the COVID-19 pandemic, by month and for 2020 and 2021, and analyse their estimates across the WHO member states, with 14.83 million global excess deaths estimated.
The zebrafish segmentation clock drives sequential segmentation of somites by periodically lowering double-phosphorylated Erk and therefore projecting its oscillation on the double-phosphorylated Erk gradient.
Using both bottom-up and top-down approaches, the record high increase in the methane growth rate in 2020 is attributed mainly to emissions from wetlands, which have been exacerbated by a warmer and wetter climate, and to the reduced atmospheric methane sink, in response to emissions reduction of air pollutants during COVID-19 lockdowns.
An array of 2D crystals of isotropic, 432-symmetric chiral gold nanoparticles is shown to exhibit collective resonances with a strong and uniform chiral near field, allowing enantioselective detection by the collective circular dichroism.
A population of highly interconnected cells in glioblastoma makes these tumours resistant to general damage but vulnerable to targeted disruption of this small fraction of cells and their rhythmic Ca2+ oscillations.
It is demonstrated that the brain circuitry involved in regulating the motivation for physical activity is not strictly central nervous system autonomous but is shaped by peripheral influences that originate in the intestinal microbial community.
Logged forests in Borneo have higher energy flow from vegetation to and broad range of bird and mammal species relative to old-growth forests and oil palm plantations, showing that they can be diverse and ecologically vibrant ecosystems.
Mutations in the sodium/iodide symporter (NIS) cause congenital hypothyroidism, and our results yield insights into how NIS selects, couples and translocates anions, thereby establishing a framework for understanding NIS function.
A study reports the distribution, replication and persistence of SARS-CoV-2 throughout the human body including in the brain at autopsy from acute infection to more than seven months following symptom onset.
Valentini et al. devise a method through which they can perform both tunnelling spectroscopy and Coulomb blockade spectroscopy on the same hybrid nanowire island to reduce ambiguities in the detection of Majorana.
In-depth transcriptomic analyses of 56,636 single cells from monkey embryos revealed transcriptional features of major perigastrulation cell types, and comparative analyses with mouse embryos and human embryoids uncovered conserved and divergent features of perigastrulation development across species.
Single-cell transcriptomic profiling and functional assays are used to identify subpopulations of eosinophils that are present in the mouse gastrointestinal tract and provide insight into the role of these cells in inflammatory bowel diseases in humans.
Synthetic cell adhesion molecules yield customized cell–cell interactions with adhesion properties that are similar to native interactions, and offer abilities for cell and tissue engineering and for systematically studying multicellular organization.
