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  • Correspondence
  • Special issue: Renal denervation: Evidence and challenges in clinical practice
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Underestimation of renal artery lumen diameter by computed tomography has consequences for the assessment of patient eligibility for renal denervation

Hypertension Research (2024)Cite this article

Recently, measuring lumen diameter (LD) of renal artery (RA) became relevant with the introduction of renal denervation (RDN) as a treatment for hypertension. This LD is one of the anatomical inclusion criteria in trials on RDN. For example, the inclusion criterion in the REQUIRE study is a LD of main RA ≥ 4 mm and <8 mm. Cases with an accessory RA with an LD ≥ 2 mm and <4 mm are excluded [1, 2] because of the variation of devices.

Our findings in the case presented here indicate that patients who are eligible for RDN might be excluded if decisions are based only on CTA. Similar cases are often seen. Because the number of eligible cases for RDN trial is small [3], it would be disappointing if cases were excluded because CTA erroneously identified anatomical problems. In the RADIANCE-HTN SOLO study, cases excluded on the basis of preoperative images accounted for as many as 17% of all exclusions [4]. This number might have included many patients who were actually eligible for the study.

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References

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Authors and Affiliations

  1. Department of Cardiology and Cardiovascular Center, Imamura Hospital, Tosu, Saga, Japan

    Keisuke Okamura & Ichiro Imamura

  2. Department of Cardiovascular Diseases, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka, Japan

    Keisuke Okamura, Masatoshi Matsushima, Shunsuke Satou, Akane Ishiya, Hideaki Shimada, Tetsu Okuda & Hidenori Urata

  3. Department of Cardiology, Fukuoka University School of Medicine, Fukuoka, Fukuoka, Japan

    Keisuke Okamura & Shin-ichiro Miura

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  1. Keisuke Okamura
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  2. Masatoshi Matsushima
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  3. Shunsuke Satou
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  4. Akane Ishiya
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  7. Ichiro Imamura
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  8. Hidenori Urata
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  9. Shin-ichiro Miura
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Correspondence to Keisuke Okamura.

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Okamura, K., Matsushima, M., Satou, S. et al. Underestimation of renal artery lumen diameter by computed tomography has consequences for the assessment of patient eligibility for renal denervation. Hypertens Res (2024). https://doi.org/10.1038/s41440-024-01718-3

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  • DOI: https://doi.org/10.1038/s41440-024-01718-3

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