Thank you for your thoughtful and constructive feedback on the manuscript entitled “Comparison of ChatGPT and Bing, in Response to the Home Blood Pressure Monitoring (HBPM) Knowledge Checklist” by Niko et al. [1]. We appreciate your interest in reading and the valuable insight you have provided.

First, we agree that the use of a standardized knowledge checklist in comparing reproducibility questions will increase the reliability of the assessment, in this study it was also tried that the questions used were standardized and were evaluated by experts. We will consider this approach in future evaluations of AI chatbots. Second, we acknowledge the importance of comparing chatbot responses with physicians’ responses, although in this study, experts’ opinions regarding chatbot responses were carefully examined. Third, we agree that trials for real-world evaluation of patient outcomes can accurately demonstrate the application of these tools. We will consider this in our future studies. We agree that it is necessary to check the lower-ranked answers by ChatGPT and improve the model. We will explore this possibility in future studies. Once again, we appreciate your comments and will consider your suggestions in future studies.