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| Open AccessA common computational principle for vibrotactile pitch perception in mouse and human
The features of vibrations provide key information on the surrounding environment. Here the authors show that a common computational principle underlies vibrotactile pitch perception in both mice and humans.
- Mario Prsa
- , Deniz Kilicel
- & Daniel Huber
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Article
| Open AccessMechanosensory neurons control sweet sensing in Drosophila
How different sensory modalities interact to control feeding is poorly understood. Here, authors show that in Drosophila, activation of labellar mechanosensory neurons causes inhibition of sweet-sensing gustatory receptor neurons, as a result, Drosophilaprefer soft food at the expense of sweetness.
- Yong Taek Jeong
- , Soo Min Oh
- & Seok Jun Moon
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Article
| Open AccessTuning Piezo ion channels to detect molecular-scale movements relevant for fine touch
The stomatin domain protein STOML3 is required for the sensation of touch. Here, Poole et al.show that STOML3 enhances the activity of mechanosensitive Piezo1 and Piezo2 ion channels by reducing their activation thresholds, and that it achieves this through its stomatin domain.
- Kate Poole
- , Regina Herget
- & Gary R. Lewin
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The neural circuits and sensory channels mediating harsh touch sensation in Caenorhabditis elegans
The mechanisms by which animals distinguish between harsh and gentle touch are unclear. UsingCaenorhabditis elegansas a model system, the authors identify neural circuits and touch-sensitive ion channels that are required for harsh touch sensation.
- Wei Li
- , Lijun Kang
- & X.Z. Shawn Xu