Letter
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Open Access
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Letter |
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
- Corine Bertolotto
- , Fabienne Lesueur
- & Brigitte Bressac-de Paillerets
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Letter |
SUMO1-dependent modulation of SERCA2a in heart failure
- Changwon Kho
- , Ahyoung Lee
- & Roger J. Hajjar
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Letter |
Listeria monocytogenes impairs SUMOylation for efficient infection
SUMOylation is a post-translational protein modification that affects many eukaryotic cellular processes. It is shown here that cellular infection with Listeria monocytogenes induces degradation of one of the essential SUMOylation enzymes, Ubc9, through a mechanism that involves a bacterial toxin, listeriolysin O. This effect on SUMOylation may support efficient infection by Listeria.
- David Ribet
- , Mélanie Hamon
- & Pascale Cossart