Featured
-
-
Article
| Open AccessMultidimensional cerebellar computations for flexible kinematic control of movements
Moving precisely in natural environments requires adapting to multiple demands arising dynamically. Here, the authors show that the cerebellum’s capacity for multidimensional computations allows it to flexibly control multiple movement parameters guaranteeing movement precision.
- Akshay Markanday
- , Sungho Hong
- & Peter Thier
-
Article
| Open AccessTopographic organization of eye-position dependent gain fields in human visual cortex
It is not fully understood how sensory ambiguity introduced by eye movements is resolved by the visual system. Here, the authors use an encoding model to capture gain modulation of visual responses in 7 T fMRI data.
- Jasper H. Fabius
- , Katarina Moravkova
- & Alessio Fracasso
-
Article
| Open AccessV1-bypassing suppression leads to direction-specific microsaccade modulation in visual coding and perception
How microsaccades modulate visual coding and perception remains incompletely understood. Here, the authors identify an emerging suppression specific to microsaccade directions that alters responses in macaque V2 and impacts perceptual decisions.
- Yujie Wu
- , Tian Wang
- & Dajun Xing
-
Article
| Open AccessOculomotor freezing reflects tactile temporal expectation and aids tactile perception
The oculomotor system keeps the eyes steady in expectation of visual events, inhibiting small fixational eye movements. Here, the authors reveal that this oculomotor freezing reflects tactile temporal expectations and aids tactile perception.
- Stephanie Badde
- , Caroline F. Myers
- & Marisa Carrasco
-
Article
| Open AccessMemory-guided microsaccades
Microsaccades are small-amplitude, fixational eye movements that are largely thought to be involuntary. Here, the authors demonstrate that monkeys (and humans) can be easily trained to respond to a remembered target location with a volitional microsaccade, and that a population of superior colliculus neurons is selectively associated with them.
- Konstantin F. Willeke
- , Xiaoguang Tian
- & Ziad M. Hafed
-
Article
| Open AccessFunctional ultrasound imaging of the brain reveals propagation of task-related brain activity in behaving primates
Neuroimaging modalities such as MRI and EEG are able to record brain activity, but spatiotemporal resolution and sensitivity are limited. Here, the authors show how a recently developed method, functional ultrasound imaging (fUS), can measure brain activation during cognitive tasks in primates.
- Alexandre Dizeux
- , Marc Gesnik
- & Mickael Tanter
-
Article
| Open AccessDissecting the circuit for blindsight to reveal the critical role of pulvinar and superior colliculus
Blindsight refers to visual behaviours that are spared following lesions to the primary visual cortex and is thought to involve pulvinar circuits. Here, the authors report that selective inactivation of the ventral pulvinar or the superior colliculus leads to impairment in visually guided saccades in blindsight.
- Masaharu Kinoshita
- , Rikako Kato
- & Tadashi Isa
-
Article
| Open AccessSaccade metrics reflect decision-making dynamics during urgent choices
Saccades have been extensively used to report choices in perceptual decision making studies yet little is known about the influence of covert decision-related processes on saccade metrics. Here, the authors demonstrate that saccade kinematics is a reliable tell about the degree of decision certainty.
- Joshua A. Seideman
- , Terrence R. Stanford
- & Emilio Salinas
-
Article
| Open AccessSpatial frequency sensitivity in macaque midbrain
In primates, the superior colliculus (SC) contributes to rapid visual exploration with saccades. Here the authors show that the superior colliculus preferentially represents low spatial frequencies, which are the most prevalent in natural scenes.
- Chih-Yang Chen
- , Lukas Sonnenberg
- & Ziad M. Hafed
-
Article
| Open AccessSaccade-synchronized rapid attention shifts in macaque visual cortical area MT
Saccades result in remapping the neural representation of a target object as well as its attentional modulation. Here the authors show that the trans-saccadic attentional shift is precisely synchronized with the saccade resulting in optimal maintenance of the locus of spatial attention.
- Tao Yao
- , Stefan Treue
- & B. Suresh Krishna
-
Article
| Open AccessEvidence for a task-dependent switch in subthalamo-nigral basal ganglia signaling
Basal ganglia can both facilitate or inhibit movement through excitatory and inhibitory pathways; however whether these opposing signals are dynamically regulated during behavior is not known. Here the authors use multinucleus LFP recordings and electrical microstimulation in monkeys performing saccade based tasks to show task specific changes in the tonic weighting of these pathways.
- Jay J. Jantz
- , Masayuki Watanabe
- & Douglas P. Munoz
-
Article
| Open AccessHeading representations in primates are compressed by saccades
Macaque higher visual areas MST and VIP encode heading direction based on self-motion stimuli. Here the authors show that, while making saccades, the heading direction decoded from the neural responses is compressed toward straight-ahead, and independently demonstrate a perceptual illusion in humans based on this perisaccadic decoding error.
- Frank Bremmer
- , Jan Churan
- & Markus Lappe
-
Article
| Open AccessSensorimotor computation underlying phototaxis in zebrafish
Active locomotion requires closed-loop sensorimotor co ordination between perception and action. Here the authors show using behavioural, imaging and modelling approaches that gaze orientation during phototaxis behaviour in larval zebrafish is related to oscillatory dynamics of a neuronal population in the hindbrain.
- Sébastien Wolf
- , Alexis M. Dubreuil
- & Georges Debrégeas
-
Article
| Open AccessSaccadic modulation of stimulus processing in primary visual cortex
Primates acquire visual information through rapid saccadic eye movements, although little is known about their effects on neural processing of visual inputs. Here the authors demonstrate that saccades produce modulations of visual cortical processing that likely originate in the thalamus.
- James M. McFarland
- , Adrian G. Bondy
- & Daniel A. Butts
-
Article
| Open AccessV1 neurons respond differently to object motion versus motion from eye movements
A key question in neuroscience is understanding how the brain distinguishes self-generated motion from motion in the external world. Here the authors demonstrate that the response of primary visual cortical neurons to a moving stimulus depends on whether the motion was self- or externally generated.
- Xoana G. Troncoso
- , Michael B. McCamy
- & Susana Martinez-Conde