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Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults
In a dose-escalation study of the COVID-19 RNA vaccine BNT162b1 in 45 healthy adults, RBD-binding IgG concentrations and SARS-CoV-2 neutralizing titres in sera increased with dose level and after a second vaccine dose.
- Mark J. Mulligan
- , Kirsten E. Lyke
- & Kathrin U. Jansen
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Review Article |
Challenges and opportunities in controlling mosquito-borne infections
- Neil M. Ferguson
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Article |
A randomized trial of normothermic preservation in liver transplantation
Normothermic machine perfusion of the liver improved early graft function, demonstrated by reduced peak serum aspartate transaminase levels and early allograft dysfunction rates, and improved organ utilization and preservation times, although no differences were seen in graft or patient survival.
- David Nasralla
- , Constantin C. Coussios
- & Peter J. Friend
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Outlook |
Perspective: The clinical trial barriers
To investigate traditional Asian medicines properly, we need to rethink the way they are tested, say Liang Liu, Elaine Lai-Han Leung and Xiaoying Tian.
- Liang Liu
- , Elaine Lai-Han Leung
- & Xiaoying Tian