Phosphoinositol signalling articles within Nature

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  • Letter |

    Phosphoinositides are important regulators of intracellular membrane traffic, and although the role of PI(4,5)P2 has been well characterised, the function of PI(3,4)P2 remains unclear; here the formation of PI(3,4)P2 by the class II phosphatidylinositol-3-kinase C2α enzyme is shown to control clathrin-mediated endocytosis.

    • York Posor
    • , Marielle Eichhorn-Gruenig
    •  & Volker Haucke
  • Brief Communications Arising |

    • Taufiq Rahman
    • , Alexander Skupin
    •  & Colin W. Taylor