Featured
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Article |
A sensory appendage protein protects malaria vectors from pyrethroids
The leg-enriched sensory appendage protein, SAP2, confers pyrethroid resistance to Anopheles gambiae, through high-affinity binding of pyrethroid insecticides; an observed selective sweep in field mosquitoes mirrors the increasing resistance reported in Africa.
- Victoria A. Ingham
- , Amalia Anthousi
- & Hilary Ranson
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Letter |
A widespread coral-infecting apicomplexan with chlorophyll biosynthesis genes
A newly identified lineage of apicomplexans, named corallicolids, are intracellular symbionts of many coral species, and possesses a plastid that retains genes for chlorophyll biosynthesis despite lacking photosystem genes.
- Waldan K. Kwong
- , Javier del Campo
- & Patrick J. Keeling
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Letter |
Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing
Next-generation sequencing is used here to analyse Plasmodium falciparum genome variation directly from clinical blood samples, as well as cultured isolates, from Africa, Asia and Oceania.
- Magnus Manske
- , Olivo Miotto
- & Dominic P. Kwiatkowski
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Article |
Origin of the human malaria parasite Plasmodium falciparum in gorillas
The evolutionary origin of the human malaria parasite Plasmodium falciparum has been much debated. Genetic analysis of a large number of faecal samples from wild-living African apes now shows that Plasmodium parasites from Western gorillas are most closely related to the human parasite. The data suggest that human P. falciparum evolved from a gorilla parasite after a single host transfer event.
- Weimin Liu
- , Yingying Li
- & Beatrice H. Hahn
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News |
Human malarial parasite came from gorillas
The parasite that causes the deadliest form of malaria in humans was not transmitted by chimpanzees.
- Joseph Milton
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Short tRNA anticodon stem and mutant eRF1 allow stop codon reassignment