Metabolic bone disease articles within Nature

Featured

• Article | 05 September 2018

  Coupling of bone resorption and formation by RANKL reverse signalling

  Osteoclasts secrete small extracellular vesicles that stimulate osteoblasts, promoting bone formation via receptor activator of nuclear factor-kappa B ligand (RANKL), thereby linking bone formation and resorption.

  • Yuki Ikebuchi
  • , Shigeki Aoki
  •  & Hiroshi Suzuki

• News & Views | 02 May 2012

  Double protection for weakened bones

  The protein Sema3A both restrains bone degradation and stimulates bone building in mice, suggesting a potential therapy for conditions such as osteoporosis. See Article p.69

  • Mone Zaidi
  •  & Jameel Iqbal

• News | 16 February 2012

  Wireless drug implant takes the trouble out of treatment

  Microchip releases doses automatically, removing need for injections.

  • Duncan Graham-Rowe

• Review Article | 18 January 2012

  The contribution of bone to whole-organism physiology

  • Gérard Karsenty
  •  & Mathieu Ferron

• News | 29 September 2010

  Bone-disease drug could treat breast cancer

  Hormone therapy causes cancer through a molecule already implicated in osteoporosis.

  • Ewen Callaway