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| Open AccessA ferroptosis-targeting ceria anchored halloysite as orally drug delivery system for radiation colitis therapy
Radiation colitis is a major side effect for pelvic radiotherapy patients, but there are limited available treatments. Here, the authors use a halloysite clay based material for the alleviation of radiation colitis in mice by inhibiting ferroptosis.
- Yue Feng
- , Xiang Luo
- & Mingxian Liu
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| Open AccessA holistic view on the role of egg yolk in Old Masters’ oil paints
Old Masters used paints containing mixtures of oils and proteins, but we lack an understanding on how and why proteins were used. Here, the authors use egg yolk in combination with two pigments to evaluate how different repartition of proteinaceous binder can be used to control the flow behaviour as well as drying kinetics and chemistry of oil paints.
- Ophélie Ranquet
- , Celia Duce
- & Norbert Willenbacher
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| Open AccessMultifaceted mechanisms mediating cystine starvation-induced ferroptosis
The cyst(e)ine/glutathione (GSH)/glutathione peroxidase 4 (GPX4) axis is the most frequently targeted pathway to trigger the ferroptosis cascade and suppress tumor growth. Two recent studies present additional mechanisms underlying cystine starvation-induced ferroptosis apart from impaired GSH synthesis.
- Zhennan Shi
- , Nathchar Naowarojna
- & Yilong Zou