Hepatitis B virus articles within Nature

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• Article | 17 May 2022

  Structure of the bile acid transporter and HBV receptor NTCP

  Cryo-electron microscopy structures of the bile acid transporter NTCP in the apo state and in complex with the preS1 domain of hepatitis B virus (HBV) provide insight into NTCP substrate transport and HBV recognition mechanisms.

  • Jinta Asami
  • , Kanako Terakado Kimura
  •  & Umeharu Ohto

• Article
  11 May 2022 | Open Access

  Structural basis of sodium-dependent bile salt uptake into the liver

  Structural studies of human Na⁺–taurocholate co-transporting polypeptide in complex with nanobodies reveal mechanisms for bile salts transport and HBV recognition involving an open-pore intermediate state.

  • Kapil Goutam
  • , Francesco S. Ielasi
  •  & Nicolas Reyes

• Article | 26 January 2022

  Petabase-scale sequence alignment catalyses viral discovery

  Serratus, an open-source cloud-computing infrastructure, can be used to screen millions of nucleic acid sequencing libraries at the petabase scale, and has enabled many new RNA viruses to be identified efficiently.

  • Robert C. Edgar
  • , Brie Taylor
  •  & Artem Babaian