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Glycoproteins are glycoconjugates of proteins, generated by glycosylation. Generally, the carbohydrate chain is long, linking numerous monosaccharides by either N-linked or O-linked glycosylation, named according to the amino acid atom to which the carbohydrate chain is attached. Glycoproteins are involved in nearly all biological processes.
Microfibrillar-associated protein 4 (MFAP4) is involved in fibrotic and cardiovascular diseases. Wozny et al. reveal structural aspects mediating MFAP4 octamer formation critical for its interaction with elastogenic proteins and cells.