Ectoderm articles within Nature

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• Article | 22 July 2020

  Glypicans shield the Wnt lipid moiety to enable signalling at a distance

  Genetic studies in Drosophila combined with structural analyses show that glypicans bind palmitoylate moieties in Wnt ligands, and thus shield Wnt ligands from their aqueous environments to enable them to signal to their distant receptors.

  • Ian J. McGough
  • , Luca Vecchia
  •  & Jean-Paul Vincent

• Letter | 14 September 2014

  A Hox regulatory network of hindbrain segmentation is conserved to the base of vertebrates

  Nested Hox expression domains are found in jawed vertebrates and in non-vertebrate chordates, but it is unclear whether there is a link between brain regionalization and Hox expression in jawless vertebrates; here, Hox expression is shown to be integrated with hindbrain segmentation in lampreys.

  • Hugo J. Parker
  • , Marianne E. Bronner
  •  & Robb Krumlauf