Barrel cortex articles within Nature

Featured

  • Article |

    Electrophysiology combined with correlated light and electron microscopy confirms the long-standing assumption that the size of a synapse is proportional to its strength, and reveals that neocortical synapses may have greater computational capacity than thought.

    • Simone Holler
    • , German Köstinger
    •  & Ken J. Stratford
  • Article |

    Computational modelling, imaging and single-cell ablation in layer 2/3 of the mouse vibrissal somatosensory cortex reveals that recurrent activity in cortical neurons can drive input-specific amplification during behaviour.

    • Simon Peron
    • , Ravi Pancholi
    •  & Karel Svoboda
  • Letter |

    Whole-cell recordings in mouse somatosensory cortex in vivo show that rhythmic sensory-whisker stimulation induces long-term synaptic potentiation (LTP) in layer 2/3 (L2/3) pyramidal cells, in the absence of somatic spikes, through long-lasting NMDAR-mediated depolarizations that are generated by synaptic networks originating from the posteromedial complex of the thalamus.

    • Frédéric Gambino
    • , Stéphane Pagès
    •  & Anthony Holtmaat
  • Letter |

    In the mouse whisker region of primary somatosensory cortex (S1), neurons projecting to secondary somatosensory cortex (S2) and primary motor cortex (M1), respectively, are differentially activated during distinct whisker-based behavioural tasks; sensory stimulus features alone do not elicit these differences, suggesting that selective transmission of S1 information to S2 and M1 is driven by behaviour.

    • Jerry L. Chen
    • , Stefano Carta
    •  & Fritjof Helmchen