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Article |
Recurrent interactions in local cortical circuits
Computational modelling, imaging and single-cell ablation in layer 2/3 of the mouse vibrissal somatosensory cortex reveals that recurrent activity in cortical neurons can drive input-specific amplification during behaviour.
- Simon Peron
- , Ravi Pancholi
- & Karel Svoboda
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Letter |
Sensation, movement and learning in the absence of barrel cortex
Mice can learn to detect objects with their whiskers and respond appropriately even in the absence of their primary somatosensory cortex.
- Y. Kate Hong
- , Clay O. Lacefield
- & Randy M. Bruno
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Letter |
Sensory-evoked LTP driven by dendritic plateau potentials in vivo
Whole-cell recordings in mouse somatosensory cortex in vivo show that rhythmic sensory-whisker stimulation induces long-term synaptic potentiation (LTP) in layer 2/3 (L2/3) pyramidal cells, in the absence of somatic spikes, through long-lasting NMDAR-mediated depolarizations that are generated by synaptic networks originating from the posteromedial complex of the thalamus.
- Frédéric Gambino
- , Stéphane Pagès
- & Anthony Holtmaat
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Letter |
Behaviour-dependent recruitment of long-range projection neurons in somatosensory cortex
In the mouse whisker region of primary somatosensory cortex (S1), neurons projecting to secondary somatosensory cortex (S2) and primary motor cortex (M1), respectively, are differentially activated during distinct whisker-based behavioural tasks; sensory stimulus features alone do not elicit these differences, suggesting that selective transmission of S1 information to S2 and M1 is driven by behaviour.
- Jerry L. Chen
- , Stefano Carta
- & Fritjof Helmchen