Arrhythmias articles within Nature

Featured

• Article | 04 November 2020

  Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia

  Heart atria produce a large pool of calcitonin (previously well-recognized as a thyroid-secreted hormone with roles in calcium and bone metabolism) that in the heart acts as a paracrine signal controlling atrial fibrosis and fibrillation.

  • Lucia M. Moreira
  • , Abhijit Takawale
  •  & Svetlana Reilly

• Letter | 21 February 2018

  Electromechanical vortex filaments during cardiac fibrillation

  Using optical mapping and 3D ultrasound, the dynamics and interactions between electrical and mechanical phase singularities were analysed by simultaneously measuring the membrane potential, intracellular calcium concentration and mechanical contractions of the heart during normal rhythm and fibrillation.

  • J. Christoph
  • , M. Chebbok
  •  & S. Luther

• Letter | 29 September 2013

  Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation

  CaMKII is known to be pathologically activated in heart failure and arrhythmias; here it is shown that glucose-induced CaMKII activation via O-linked glycosylation might contribute to cardiac pathology in diabetes.

  • Jeffrey R. Erickson
  • , Laetitia Pereira
  •  & Donald M. Bers

• Outlook | 30 January 2013

  Physiology: Beating stroke

  New drugs and more focused therapy might cut down on atrial fibrillation and reduce the incidence of stroke.

  • Neil Savage

• Letter | 27 January 2013

  Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs

  This study demonstrates that an inheritable adult onset heart disease can be modelled in vitro within months with the help of metabolic maturation induction.

  • Changsung Kim
  • , Johnson Wong
  •  & Huei-Sheng Vincent Chen

• Letter | 22 February 2012

  Circadian rhythms govern cardiac repolarization and arrhythmogenesis

  Circadian rhythmicity of cardiac ion-channel expression and of an index of myocardial repolarization is under the control of Klf15, a clock-dependent oscillator that is required for generating transient outward potassium current, and deficiencies or excesses of which cause loss of rhythmic variation in myocardial and abnormal repolarization, and an enhanced susceptibility to ventricular arrhythmias.

  • Darwin Jeyaraj
  • , Saptarsi M. Haldar
  •  & Mukesh K. Jain

• News & Views | 13 July 2011

  Several small shocks beat one big one

  Life-threatening abnormalities in the electrical rhythm of the heart are usually treated with the application of a large electric shock. An approach involving a significantly smaller shock energy may be equally effective. See Letter p.235

  • Richard A. Gray
  •  & John P. Wikswo

• News | 13 July 2011

  A kinder, gentler defibrillator

  A new technique could lower the intensity of the shock needed to reset electrical instabilities in the heart.

  • Alla Katsnelson

• Letter | 13 July 2011

  Low-energy control of electrical turbulence in the heart

  • Stefan Luther
  • , Flavio H. Fenton
  •  & Eberhard Bodenschatz