News & Comment

A physicist handy with charcoal and ink uses sculpted light to image the brain.

A chemist who illuminated biology.

Appeal to intuition when making value judgments

Constraining the magnitude of parameters of a model can control its complexity

A chemist intrigued by DNA and RNA structure and two-wheeled mountainous ascents.

Sequins can help labs see how well a sequencing experiment is going. Surfing experiments are another matter.

With four parameters I can fit an elephant and with five I can make him wiggle his trunk. —John von Neumann

To the tune of a classical guitar, finding a way to watch learning as it happens.

It is important to understand both what a classification metric expresses and what it hides.

A new near-infrared optogenetic system and science as a family business.

Regression can be used on categorical responses to estimate probabilities and to classify.

Limitations in print resolution and visual acuity impose limits on data density and detail.

A bleaching method for glycobiology and some impromptu fund-raising at the piano.

Residual plots can be used to validate assumptions about the regression model.

Measuring phosphoproteins reproducibly and taking time to bike.

Team sports and team efforts lead to a new tool that helps with immune profiling.

Some outliers influence the regression fit more than others.

Skiing his way to multiplexed imaging.

Use alignment and consistency to untangle complex circuit diagrams.