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  • Methods for imaging multiple targets in a single cell are breaking the color barrier.

    • Rita Strack
    Method to Watch
  • Methods to systematically map the distribution of proteins in cells are evolving.

    • Natalie de Souza
    Method to Watch
  • New approaches are needed to see the dynamics of 3D chromatin structure at high resolution and throughput.

    • Nicole Rusk
    Method to Watch
  • Optogenetic manipulation of neurons at cellular resolution holds promise for the dissection of neural microcircuitry.

    • Nina Vogt
    Method to Watch
  • New computational tools learn complex motifs from large sequence data sets.

    • Nicole Rusk
    Method to Watch
  • Integrated molecular profiles of single cells will provide mechanistic insights into gene regulation and heterogeneity.

    • Tal Nawy
    Method to Watch
  • Advances in time-resolved crystallography make it possible to follow ever more rapid protein structural changes.

    • Allison Doerr
    Method to Watch