News & Comment

Methods for tackling the enormously complex glycoproteome are sorely needed.

Improved single-cell methods are helping to unravel biological complexity.

The revival of light-sheet microscopy opens new possibilities for the imaging of living processes.

Genetically encoded voltage sensors are finally measuring up.

Tools to manipulate murine genes on a genome-wide scale and to phenotype their effects in animals are maturing.

Sequencing a haploid genome and understanding the impact of its variants requires technical and computational improvements.

Next-generation sequencing is broadening the application of genetic and genomic studies to the panoply of life.

Accurate methods for RNA-structure determination are being developed.