News & Comment

A metagenomic approach to identifying the sources of N⁶-methyldeoxyadenine (6mA) in eukaryotic DNA found no evidence of high 6mA abundances in sampled eukaryotes.

Two groups report improved variants of the channelrhodopsins ChRmine and ChroME, respectively.

Jellyfish are established as a model system for neuroscience.

Slide-DNA-seq enables profiling of spatially resolved mutations and clonal populations in intact tumor samples.

Clonal evolution of stem cells unveiled by modeling DNA methylation fluctuation.

An imaging mass cytometry method reconstructs tissue microenvironments in 3D.

Researchers push the limits of confocal microscopy by combining multiple views, super-resolution and deep learning.

MapToCleave enables the large-scale study of miRNA precursor processing in living cells.

Frequencies of passenger mutations hint at unobserved driver mutations.

The first single-cell transcriptome of the gastrulating human embryo.

Two studies use nanopores for single-protein fingerprinting and make headway toward single-protein sequencing.

Two microscopy approaches bring flexibility to mesoscopic imaging in the brain, allowing independent imaging in multiple regions simultaneously.