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Nature Medicine 14, 13 - 14 (2008)
doi:10.1038/nm0108-13
Opening the gateway to tumors
Michael H Kershaw1
- Michael H. Kershaw is in the Cancer Immunology Research Program, Peter MacCallum Cancer Centre, St. Andrews Place, Melbourne, Victoria 3002, Australia. e-mail: michael.kershaw@petermac.org
Abstract
T cells can turn back cancer, but they don't always reach tumor cells in sufficient numbers to do so. A close look at the cells of tumor blood vessels suggests a way to boost T cell migration in individuals with cancer (pages 28–36).
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RESEARCH
Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapyNature Medicine Article (01 Jan 2008)