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Tamoxifen and its analogues are powerful tools in the fight against breast cancer and may soon find applications fighting other diseases such as atherosclerosis and osteoporosis.
The discovery of hyperhomocysteinemia as a major factor in the pathogenesis of arteriosclerosis offers new strategies and opportunities for prevention and treatment.
The brain is an isolated metabolic preserve and small metabolic biases that may have no consequences for other cells may have an important role in many neurological conditions.
Bosnia and Herzegovina and Croatia are well-known endemic regions of hemorrhagic fever with renal syndrome (HFRS). We can expect that HFRS infections will be a hazard to NATO peace-keeping forces.
The gene therapy community has swung from an excited and overoptimistic mood to one of disillusionment with the apparent slowness of progress and with the absence of truly therapeutic applications. Although gene therapy is yet to come of age, there can be no doubt that, in time, it will bear fruit.
Glutamic acid decarboxylase is attracting much interest because of its putative involvement in two clinical disorders: stiff-man syndrome and insulin-dependent diabetes. Here we discuss the clinical significance of an autoimmune response against CAD and consider how such information may help identify the disease mechanisms of these disorders.
Reduced intake of food and enhanced physical activity, the main behavioral manifestations of self-starvation and anorexia nervosa, activate brain substrates associated with reward.
The infectious disease risks associated with baboon-to-human transplants may represent an insurmountable hurdle in the race to save lives. Yet, public health agencies are relucant to regulate Xenotransplantation in spite of those risks.