Studies that have provided the first unbiased, large-scale analyses of DNA mutations across an array of cancers also have lessons for the proposal to annotate the entire cancer genome.
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References
Greenman, C. et al. Nature 446, 153–158 (2007).
Stephens, P. et al. Nature Genet. 37, 590–592 (2005).
Stephens, P. et al. Nature 431, 525–526 (2004).
Hunter, C. et al. Cancer Res. 66, 3987–3991 (2006).
Sjöblom, T. et al. Science 314, 268–274 (2006).
Kantarjian, H. et al. N. Engl. J. Med. 346, 645–652 (2002).
Davies, H. et al. Nature 417, 949–954 (2002).
von Eschenbach, A. & Collins, F. http://cancergenome.nih.gov/about/TCGA_executive_summary.pdf (2005).
Lynch, T. J. et al. N. Engl. J. Med. 350, 2129–2139 (2004).
Paez, J. G. et al. Science 304, 1497–1500 (2004).
Weinstein, I. B. Science 297, 63–64 (2002).
Pinkel, D. & Albertson, D. G. Annu. Rev. Genomics Hum. Genet. 6, 331–354 (2005).
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Haber, D., Settleman, J. Drivers and passengers. Nature 446, 145–146 (2007). https://doi.org/10.1038/446145a
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DOI: https://doi.org/10.1038/446145a
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