Constraining conformation
Peptide stapling improves stability and enhances binding. Non-symmetric stapling greatly expands the applicability of the approach, but introduces challenges of chemoselectivity and site-selectivity.
Peptide stapling improves stability and enhances binding. Non-symmetric stapling greatly expands the applicability of the approach, but introduces challenges of chemoselectivity and site-selectivity.
Colloid science has developed through innovative use of silane coupling agents. We highlight the advances in complex colloid synthesis, focussing on 3-trimethoxysilylpropyl methacrylate (TPM) and related compounds. We outline the remarkable properties, unique synthesis strategies and ensuing pioneering applications of TPM colloids.