Single-cell GET-seq (scGET-seq) enables the probing of compacted as well as accessible chromatin in single cells, covering a greater portion of the genome, which provides insights into genomic and epigenetic dynamics.
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Tedesco, M. et al. Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin. Nat. Biotechnol. https://doi.org/10.1038/s41587-021-01031-1 (2021).
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Tang, L. Sketching open and closed chromatin. Nat Methods 18, 1448 (2021). https://doi.org/10.1038/s41592-021-01351-9
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DOI: https://doi.org/10.1038/s41592-021-01351-9