Our work identifies previously unrecognized functional heterogeneity in tissue-resident interstitial macrophages. We have identified ten macrophage subsets, each thought to specifically contribute to recruiting and organizing cell types within tissues. Moreover, our findings suggest the diversity and division of labor extend to other macrophage populations previously considered homogeneous.
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References
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This is a summary of: Li, X. et al. Coordinated chemokine expression defines macrophage subsets across tissues. Nat. Immunol. https://doi.org/10.1038/s41590-024-01826-9 (2024).
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The hidden functional diversity of macrophages. Nat Immunol (2024). https://doi.org/10.1038/s41590-024-01832-x
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DOI: https://doi.org/10.1038/s41590-024-01832-x
