Injury or infection renders patients vulnerable to secondary pneumonia. A new study indicates that SIRP-α triggers prolonged impairment of the phagocytic capacity of alveolar macrophages after the resolution of primary bacterial or viral pneumonia.
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de Vos, A.F., van der Poll, T. SIRP-α instructs alveolar macrophages to stop eating after pneumonia. Nat Immunol 21, 601–603 (2020). https://doi.org/10.1038/s41590-020-0680-y
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DOI: https://doi.org/10.1038/s41590-020-0680-y
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Immune cell composition of the bronchoalveolar lavage fluid in healthy and respiratory diseased dromedary camels
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