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Neuroinflammation

Skipping adolescence to become super-inflammatory monocytes

Nature Immunology volume 21, pages 491–492 (2020)Cite this article

Single-cell RNA-sequencing of myeloid cells during neuroinflammation identifies a new population of pathogenic Cxcl10-expressing phagocytes, which develop independently of Ly6Chi monocytes but derive from early myeloid precursors shaped by the inflamed tissue microenvironment.

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Fig. 1: Profiling the CNS-invading mononuclear phagocytes.

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Authors and Affiliations

  1. Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland

    Burkhard Becher, Donatella De Feo, Ana Amorim & Melanie Greter

Authors
  1. Burkhard Becher
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  2. Donatella De Feo
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  3. Ana Amorim
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  4. Melanie Greter
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Correspondence to Melanie Greter.

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The authors declare no competing interests.

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Becher, B., De Feo, D., Amorim, A. et al. Skipping adolescence to become super-inflammatory monocytes. Nat Immunol 21, 491–492 (2020). https://doi.org/10.1038/s41590-020-0652-2

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