Following internalization of an actin-bearing ligand, the C-type lectin receptor DNGR-1 promotes phagosome rupture, allowing antigens to access the cytosol and be processed through the MHC-I pathway.
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Hatinguais, R., Brown, G.D. Cross-presentation is getting DNGRous. Nat Immunol 22, 108–110 (2021). https://doi.org/10.1038/s41590-020-00831-y
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DOI: https://doi.org/10.1038/s41590-020-00831-y
