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NK CELLS

How to wake a killer

Manipulating the mitochondrial morphology of exhausted tumor-derived NK cells restores their metabolic fitness and function.

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Fig. 1: Common phenotype of mitochondrial dysfunction in TINK cells and hypoxic NK cells.

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Correspondence to Clair M. Gardiner.

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Gardiner, C.M. How to wake a killer. Nat Immunol 20, 1561–1563 (2019). https://doi.org/10.1038/s41590-019-0541-8

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