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Is clonal hematopoiesis ‘mostly harmless’?

Nature Genetics volume 55, pages 2029–2030 (2023)Cite this article

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Whole-genome sequencing data of individuals from the UK Biobank and Iceland and a somatic mutation barcoding strategy enabled detection of clonal hematopoiesis at scale. This comprehensive study provides insights into the epidemiology, somatic and germline genetics, and disease associations of clonal hematopoiesis.

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Fig. 1: CH and risks of hematological neoplasia.

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This is a summary of: Stacey, S. N. et al. Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis. Nat. Genet. https://doi.org/10.1038/s41588-023-01555-z (2023).

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Is clonal hematopoiesis ‘mostly harmless’?. Nat Genet 55, 2029–2030 (2023). https://doi.org/10.1038/s41588-023-01556-y

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