Abstract
Using a highly specific chemical reaction, investigators at the University of California at Berkeley have developed an innovative system to covalently label cell-surface sugar molecules in live mice.
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References
Prescher, J.A. et al. Chemical remodelling of cell surfaces in living animals. Nature 430, 873–877 (2004).
Saxon, E. & Bertozzi, C.R. Cell surface engineering by a modified Staudinger reaction. Science 287, 2007–2010 (2000).
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Eisenstein, M. Creating a 'sweet spot' for in vivo cell-surface tagging. Nat Methods 1, 4–5 (2004). https://doi.org/10.1038/nmeth1004-4a
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DOI: https://doi.org/10.1038/nmeth1004-4a