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A catch to integrin activation

Nature Immunology volume 8, pages 1035–1037 (2007)Cite this article

T cells interact with chemokines displayed on cells outside and inside blood vessels of the lymph node. New work shows that these chemokines exert distinct activation effects on T cell integrins depending on their mechanical environment.

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Figure 1: Biochemical and mechanical factors cooperatively regulate leukocyte adhesion.

Kim Caesar

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Authors and Affiliations

  1. Rodger P. McEver is with the Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104, USA. rodger-mcever@omrf.org,

    Rodger P McEver

  2. Cheng Zhu is in the Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.,

    Cheng Zhu

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  1. Rodger P McEver
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  2. Cheng Zhu
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McEver, R., Zhu, C. A catch to integrin activation. Nat Immunol 8, 1035–1037 (2007). https://doi.org/10.1038/ni1007-1035

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