How do T cells recognize allogeneic MHC molecules with such ferocity? The first crystal structure of an allo-MHC complexed with peptide and T cell receptor begins to reveal the answer.
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Kranz, D. Incompatible differences: view of an allogeneic pMHC-TCR complex. Nat Immunol 1, 277–278 (2000). https://doi.org/10.1038/79716
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DOI: https://doi.org/10.1038/79716