Cells of the innate and adaptive immune systems often require signals emanating from diverse cell surface receptors for full activation. For dendritic cells, synergistic stimulation by different pairs of Toll-like receptors provides the host with a mechanism to react rapidly and specifically to different pathogens.
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Malissen, B., Ewbank, J. 'TaiLoRing' the response of dendritic cells to pathogens. Nat Immunol 6, 749–750 (2005). https://doi.org/10.1038/ni0805-749
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DOI: https://doi.org/10.1038/ni0805-749
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