New data shows that NADPH oxidase activation by Rac2 involves an insert-dependent interaction between Rac2 and cyt b. This unique activation mechanism has far-reaching implications for the regulation of related signaling systems.
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Hoffman, G., Cerione, R. Rac inserts its way into the immune response. Nat Immunol 2, 194–196 (2001). https://doi.org/10.1038/85240
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DOI: https://doi.org/10.1038/85240
