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Resident memory T cells are a Notch above the rest

Nature Immunology volume 17, pages 1337–1338 (2016)Cite this article

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Notch signaling promotes the maintenance of lung-resident CD8+ memory T cells that are transcriptionally poised for rapid effector responses but have heightened expression of inhibitory receptors, suggestive of tight regulation.

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Figure 1: Human lung memory CD8+ T cells have now been shown to bear properties of TRM cells.

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Authors and Affiliations

  1. Department of Microbiology and Immunology, Sathi Wijeyesinghe and David Masopust are in the Center for Immunology, University of Minnesota, Minneapolis, Minnesota, USA.,

    Sathi Wijeyesinghe & David Masopust

Authors
  1. Sathi Wijeyesinghe
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  2. David Masopust
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Correspondence to David Masopust.

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Wijeyesinghe, S., Masopust, D. Resident memory T cells are a Notch above the rest. Nat Immunol 17, 1337–1338 (2016). https://doi.org/10.1038/ni.3617

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