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Innate TCRs: single use only

Nature Immunology volume 15, pages 12–13 (2014)Cite this article

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Innate-like T cells are dependent on triggering via the T cell antigen receptor (TCR) for development but subsequently actively alter their TCR responsiveness to allow an innate mode of activation that no longer requires TCR signaling.

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Figure 1: From ILC to T cell activation: bridging innate and adaptive immunity.

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Authors and Affiliations

  1. Tom Cupedo is in the Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.,

    Tom Cupedo

  2. Division of Gastroenterology and Nutrition, Janneke N. Samsom is in the Laboratory of Pediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands.,

    Janneke N Samsom

Authors
  1. Tom Cupedo
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  2. Janneke N Samsom
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Correspondence to Tom Cupedo.

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The authors declare no competing financial interests.

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Cupedo, T., Samsom, J. Innate TCRs: single use only. Nat Immunol 15, 12–13 (2014). https://doi.org/10.1038/ni.2792

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