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Ikaros changes the face of NuRD remodeling

The inclusion of the transcription factor Ikaros in the NuRD chromatin-remodeling complex regulates both the targeting and activity of the NuRD complex in lymphocytes, thereby influencing developmental gene-expression programs.

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Figure 1: Ikaros influences the genomic localization and functional activity of the Mi-2β NuRD complex.

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Correspondence to Amy S Weinmann.

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Oestreich, K., Weinmann, A. Ikaros changes the face of NuRD remodeling. Nat Immunol 13, 16–18 (2012). https://doi.org/10.1038/ni.2191

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