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Unraveling TACIt functions

Nature Genetics volume 37, pages 793–794 (2005)Cite this article

Primary immunodeficiencies, ranging from mild to very severe, comprise more than 50 different entities in which part of the body's immune system is missing or does not function properly. Two studies now report defects in the TNFR family member TACI associated with two forms of human immunodeficiency.

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Figure 1: Receptors for BAFF and APRIL control B cell development and function.

Katie Ris

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Authors and Affiliations

  1. Department of Immunology,

    Flavius Martin & Vishva M Dixit

  2. Department of Molecular Oncology at Genentech, 1 DNA Way, South San Francisco, 94080, California, USA

    Flavius Martin & Vishva M Dixit

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  1. Flavius Martin
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  2. Vishva M Dixit
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Martin, F., Dixit, V. Unraveling TACIt functions. Nat Genet 37, 793–794 (2005). https://doi.org/10.1038/ng0805-793

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