M Tartaglia, E L Mehler, R. Goldberg, G Zampino, H G Brunner, H Kremer, I van der Burgt, A H Crosby, A Ion, S Jeffery, K Kalidas, M A Patton, R S Kucherlapati & B D Gelb Nature Genet. 29, 465–468 (2001).

The locus for Noonan syndrome was incorrectly referred to as N-SH2, in the introductory paragraph. The third sentence of the paragraph should read: “It has been mapped to a 5-cM region (NS1) on chromosome 12q24.1, and genetic heterogeneity has also been documented3–6.”